Structure
| TCI Product No. : | T2572 | ||||||||||||||
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| Stock Status : |
Status at 02:00 a.m. on 11 Feb 2012 * Items available from stock in Japan will be delivered in 10 business days |
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| Purity / Analysis Method : | >97.0%(GC) | ||||||||||||||
| Storage : | |||||||||||||||
| M.F. / M.W. : | C6H13BO2=127.98 | ||||||||||||||
| CAS Number : | 25015-63-8 | ||||||||||||||
| Related CAS Number : | |||||||||||||||
| MDL Number : | MFCD00674030 | ||||||||||||||
| bp : | 43 °C / 50mmHg |
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| d : | 0.89 |
| fp : | 5 °C |
Borylation of Triflate with Pinacolborane Typical procedure: To a degassed solution of L-tyrosine triflate derivative (500 mg, 1.17 mmol) and NMM (0.129 mL, 1.17 mmol) in dioxane (5 mL) is added PdCl2(dppf).CH2Cl2 (4.8 mg, 0.0059 mmol) and pinacolborane (0.255 mL, 1.76 mmol) at room temperature. The reaction mixture is then stirred for 24 h at 80 ℃. After cooling to room temperature, the mixture is concentrated and directly purified by silica gel column chromatography (heptane : ethyl acetate = 3 : 1) to give the borylation product as a colorless viscous oil (445 mg, 94% yield). |
| UNNo. : | 3399 |
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| Class : | 4.3 / 3 |
| PG : | II |
| Signal Word : | Danger |
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| Pictogram : |
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| GHS H Statement : | Highly flammable liquid and vapour. In contact with water releases flammable gases. |
| GHS P Statement : | IF ON SKIN (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower. In case of fire: Do not use water for extinction. Wear protective gloves/eye protection/face protection. Store in a dry place. Store in a closed container. Keep away from heat/sparks/open flames/hot surfaces. 窶 No smoking. Use explosion-proof electrical/ventilating/lighting equipment. Take precautionary measures against ignition by the static discharge and the spark. |