1,4,7,10-Tetraazacyclododecane

Synonym : Cyclen

Structure

1,4,7,10-Tetraazacyclododecane
General Information
TCI Product No. : T1874
Stock Status :
Unit Sizes Price Available stock
Belgium Tokyo *
1G 93.50 GBP 3 >10
5G 317.90 GBP 2 >10

Status at 02:00 a.m. on 11 Feb 2012

* Items available from stock in Japan will be delivered in 10 business days
Purity / Analysis Method : >97.0%(GC)(T)
Storage : Refrigerator
M.F. / M.W. : C8H20N4=172.28
CAS Number : 294-90-6
Related CAS Number :
MDL Number :
Data of Reference
mp : 111 °C
Application

Cyclen-catalyzed Henry reaction (nitroaldol reaction)

Cyclen-catalyzed Henry reaction (nitroaldol reaction)

Typical procedure: Nitromethane (122 mg) is added to the solution of benzaldehyde (106 mg) in THF (1 mL). Then, cyclen (8.6 mg) is added. The solution is stirred at room temperature for 24 h. Volatile components are removed under reduced pressure and the residue is purified by chromatography on silica gel (eluent: pentane/diethyl ether) to give 2-nitro-1-phenylethanol (134 mg, 80 %).
References
Beilstein : 26(5)11,23
RTECS# : XA5253000
Safety
Signal Word : Danger
Pictogram : Corrosion Exclamation Mark Environment
GHS H Statement : Harmful in contact with skin and if swallowed. Causes severe skin burns and eye damage. Very toxic to aquatic life. Very toxic to aquatic life with long lasting effects.
GHS P Statement : IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF ON SKIN (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower. Do not breathe. Avoid release to the environment. Wear protective gloves/protective clothing/eye protection/face protection. IF SWALLOWED: rinse mouth. Do NOT induce vomiting.
Risk Phrases
R36/37/38 : Irritating to eyes, respiratory system and skin.
Safety Phrases
S26 : In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S36 : Wear suitable protective clothing.
Informative Links
TCI Product Literature :
Related Categories :
Functional Materials Macrocycles for Host-Guest Chemistry Crown Ethers
Biochemistry Polyamines Polyamines Cyclic Polyamines

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