Structure
| TCI Product No. : | C2422 | ||||||||||||||
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| Stock Status : |
Status at 02:00 a.m. on 11 Feb 2012 * Items available from stock in Japan will be delivered in 10 business days |
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| Purity / Analysis Method : | >97.0%(T) | ||||||||||||||
| Storage : | Freezer | ||||||||||||||
| M.F. / M.W. : | C21H24ClCuN2=403.43 | ||||||||||||||
| CAS Number : | 873779-78-3 | ||||||||||||||
| Related CAS Number : | |||||||||||||||
| MDL Number : | |||||||||||||||
(IMes)-copper complex catalyzed methylenation of cinnamaldehydes Typical procedure (R = H): To a solution of (IMes)-Cu complex catalyst (20.2 mg) and triphenylphosphine (288 mg) in dioxane (10 mL) at 25 ºC is added 2-propanol (84 micro-L) followed by trans-cinnamaldehyde (132 mg) and the trimethylsilyldiazomethane solution (1.4 – 2.0 mmol) under inert atmosphere. The resulting mixture is then heated at 60 ºC for 2 h. Afterward, 3% H2O2 (10 mL) is added and the organic layer is extracted with ether (3 x 20 mL). The combined organic layers are washed with brine (2 x 20 mL) and dried over MgSO4. The filtrate is removed under reduced pressure and the residue is purified by flash chromatography on silica gel (eluent: 1% EtOAc/hexanes) to give 1-phenyl-1,3-butadiene (100 mg, 77%) as a colorless oil. |
| Related Categories : |
Structure of Chemicals
Classes of Metal Compounds
Transition Metal Compounds
Cu (Copper) Compounds
Synthetic Organic Chemistry Catalysts for Organic Synthesis Homogeneous Catalysts Copper |
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