1,1'-Bis(diphenylphosphino)ferrocene

Synonym : 1,1'-Ferrocenebis(diphenylphosphine)

Synonym : dppf

Structure

1,1'-Bis(diphenylphosphino)ferrocene
General Information
TCI Product No. : B2027
Stock Status :
Unit Sizes Price Available stock
Belgium Tokyo *
1G 32.75 GBP 2 >10
5G 98.25 GBP 2 >10
25G 345.25 GBP 2 >10

Status at 02:00 a.m. on 11 Feb 2012

* Items available from stock in Japan will be delivered in 10 business days
Purity / Analysis Method : >96.0%(T)
Storage :
M.F. / M.W. : C34H28FeP2=554.39
CAS Number : 12150-46-8
Related CAS Number :
MDL Number : MFCD00001422
Application

Synthesis of Carbinols

Synthesis of Carbinols

Typical procedure: Under an air atmosphere, a Schlenk tube is charged with Cu(OAc)2•H2O (4.0 mg, 0.02 mmol), dppf (16.6 mg, 0.03 mmol), arylboronic acid (0.4 mmol), aldehyde (0.2 mmol), NaOAc (49.2 mg, 0.6 mmol), and toluene (3 mL) under ice-salt (-20 ºC). The mixture is stirred for 0.5 h at room temperature, refluxed for 24 h, and then cooled in a Schlenk tube to room temperature. The mixture is extracted with ethyl acetate (4×5 mL), and the organic layers are washed with water. The organic layers are dried over MgSO4, concentrated, and purified by flash column chromatography on silica gel to give the desired product.

Safety
Signal Word : Warning
Pictogram : Exclamation Mark
GHS H Statement : Harmful by inhalation, in contact with skin and if swallowed.
GHS P Statement : IF ON SKIN: Gently wash with plenty of soap and water. Avoid breathing. Wear protective gloves/protective clothing/eye protection/face protection. IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing. Call a POISON CENTER or doctor/physician if you feel unwell. Wash hands thoroughly after handling. IF SWALLOWED: Call a POISON CENTER or doctor/physician if you feel unwell. Rinse mouth.
Risk Phrases
R25 : Toxic if swallowed.
Safety Phrases
S20/21 : When using do not eat, drink or smoke.
S22 : Do not breathe dust.
S28 : After contact with skin, wash immediately with plenty of ... (to be specified by the manufacturer).
S36 : Wear suitable protective clothing.
S45 : In case of accident or if you feel unwell, seek medical advice immediately (show the lable where possible).
Informative Links
TCI MAIL :
TCI Product Literature :
Related Categories :
Structure of Chemicals Classes of Metal Compounds Transition Metal Compounds Fe (Iron) Compounds
Synthetic Organic Chemistry Suzuki-Miyaura Cross-coupling Phosphine Ligands (for Suzuki-Miyaura Cross-coupling)
Structure of Chemicals Metallocenes Ferrocenes
Synthetic Organic Chemistry Phosphines
Synthetic Organic Chemistry Ligands Phosphine Ligands

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