Updated
23 Aug 2010

Highly Diastereoselective Synthesis of Fully Substituted Tetrahydrofurans
Hu et al. have reported the synthesis of fully substituted tetrahydrofurans by a one-pot cascade reaction using a rhodium(II) catalyst. According to their results, by the reaction of an aryldiazoacetate with a secondary allyl alcohol derivative in the presence of rhodium(II) acetate dimer, an O-H insertion reaction proceeds with excellent diastereoselectivity. Subsequent intramolecular Michael-type addition produces the desired tetrahydrofurans with excellent stereoselective control.
X. Xu, X. Han, L. Yang, W. Hu, Chem. Eur. J. 2009, 15, 12604.
       ------------------------------------------

New HPLC column is now available -
"TCI Dual ODS-CX15"
Enables rapid analysis of both basic and hydrophobic compounds simultaneously!

Details

       ------------------------------------------
The new TCI catalogue
"Fine Chemicals 2010-2011" is available!
The catalogue includes more than 21,000 high quality chemicals - including 1,300+ new items.

Request your free copy!

       ------------------------------------------
Battery Materials
TCI provides various reagents to be used in research of organic solar batteries.
All products can be supplied in both reagent and bulk quantities.

Details

       ---------------------------------------
Test Reagents
TCI supplies the lineup of test reagents: quaternary ammonium compounds used in clinical chemistry, and chromogenic substrates for peroxidase.

Details